MitMAB

Tocris Bioscience | Catalog # 4224

Dynamin inhibitor
Tocris Bioscience
Discontinued Product
4224 has been discontinued. View all Dynamin Inhibitors products.

Key Product Details

Description

Dynamin inhibitor
View all Dynamin Inhibitors »

Product Description

MitMAB is a dynamin inhibitor; inhibits the GTPase activity of dynamin I (Ki = 940 nM; IC50 = 3.1 μM). Targets the dynamin-phospholipid interaction. Inhibits receptor-mediated endocytosis of epidermal growth factor (EGF) in non-neuronal cells; also inhibits synaptic vesicle endocytosis. Displays dynamin I-inhibitory activity similar to OctMAB (Cat. No. 4225).

Product Specifications for MitMAB

Molecular Weight

336.39

Formula

C17H38BrN

Storage

Desiccate at RT

Chemical Name

Tetradecyltrimethylammonium bromide

CAS Number

1119-97-7

PubChem ID

14250

InChI Key

CXRFDZFCGOPDTD-UHFFFAOYSA-M

SMILES

C[N+](C)(C)CCCCCCCCCCCCCC.[Br-]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 33.64 100

Preparing Stock Solutions for MitMAB

The following data is based on the product molecular weight 336.39.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.97 mL 14.86 mL 29.73 mL
5 mM 0.59 mL 2.97 mL 5.95 mL
10 mM 0.30 mL 1.49 mL 2.97 mL
50 mM 0.06 mL 0.30 mL 0.59 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for MitMAB

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for MitMAB

For research use only

Customer Reviews for MitMAB (1)

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  • Apoptosis was induced by MitMAB in PC3 cells
    Name: Anonymous
    Species: Human
    Verified Customer | Posted 02/11/2019
    Apoptosis was induced by MitMAB in PC3 cells. The figure shows the results from DAPI staining obtained via EVOSTM Floid Florescence Microscope X80 magnification.
    MitMAB 4224

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