OctMAB

Key Product Details

Product Description

OctMAB is a dynamin inhibitor (IC₅₀ = 1.9 μM for dynamin I). Inhibits receptor-mediated endocytosis (IC₅₀ = 16 μM). Displays similar activity to MitMAB (Cat. No. 4224).

Product Specifications for OctMAB

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for OctMAB

The following data is based on the product molecular weight 392.50.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.55 mL	12.74 mL	25.48 mL
5 mM	0.51 mL	2.55 mL	5.10 mL
10 mM	0.25 mL	1.27 mL	2.55 mL
50 mM	0.05 mL	0.25 mL	0.51 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 6 publications citing the usage of this product.

• Joshi The dynamin inhibitors MitMAB and OctMAB induce cytokinesis failure and inhibit cell proliferation in human cancer cells. Mol.Cancer Ther. 2010 PMID: 20571068
• Quan Myristyl trimethyl ammonium bromide and octadecyl trimethyl ammonium bromide are surface-active small molecule dynamin inhibitors that block endocytosis mediated by dynamin I or dynamin II. Mol.Pharmacol. 2007 PMID: 17702890

Product Documents for OctMAB