MitoPY1

  ( 4 citations )    
Product Datasheet
Catalog Number:4428
Chemical Name:[4-[4-[3-Oxo-6'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3'-yl]-1-piperazinyl]butyl]triphenyl-phosphonium iodide
Product Details
Citations (4)
Reviews
Biological Activity
Fluorescent probe for imaging hydrogen peroxide (H2O2) in mitochondria of living cells. Displays enhanced emission at 528 nm in the presence of H2O2. Selective for H2O2 over superoxide, nitric oxide and hydroxyl radical. Detects local increases in H2O2 in an in vitro model of Parkinson's Disease.
Technical Data
  • M.Wt:
    954.68
  • Formula:
    C52H53BIN2O5P
  • Solubility:
    Soluble to 100 mM in DMSO
  • Storage:
    Store at -20°C
  • CAS No:
    1041634-69-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold under license from the Regents of the University of California
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for MitoPY1 include:

4 Citations: Showing 1 - 4
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  1. Oxidized LDL-induced angiogenesis involves sphingosine 1-phosphate: prevention by anti-S1P antibody.
    Authors: Camaré Et al.
    Br J Pharmacol  2015;172:106
  2. Metabolic Damage and Premature Thymus Aging Caused by Stromal Catalase Deficiency.
    Authors: Griffith Et al.
    Cell Rep  2015;12:1071
  3. An acute rise in intraluminal pressure shifts the mediator of flow-mediated dilation from nitric oxide to hydrogen peroxide in human arterioles.
    Authors: Beyer Et al.
    Am J Physiol Heart Circ Physiol  2014;307:H1587
  4. Ceramide changes the mediator of flow-induced vasodilation from nitric oxide to hydrogen peroxide in the human microcirculation.
    Authors: Freed Et al.
    Circ Res  2014;115:525

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