Home / Cannabinoid R1/CB1 Antagonists / MJ 15

MJ 15

Catalog #: 4063
2 Citations Datasheet / COA / SDS

Discontinued Product

4063 has been discontinued.
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MJ 15 | CAS No. 944154-76-1 | Cannabinoid R1/CB1 Antagonists
1 Image
Description: Potent and selective CB1 antagonist

Chemical Name: 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(3-pyridinylmethyl)-1H-pyrazole-3-carboxamide

Purity: ≥99%

Product Details
Citations (2)
Reviews
Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

MJ 15 is a potent and selective CB1 receptor antagonist (Ki = 27.2 pM, IC50 = 118.9 pM for rat CB1 receptors). Exhibits potency in obesity and hyperlipidemia models; inhibits food intake and increases in body weight in diet-induced obese rats and mice.

Technical Data

M.Wt:
471.77
Formula:
C23H17Cl3N4O
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
944154-76-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under licence.

Product Datasheets

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Citations for MJ 15

The citations listed below are publications that use Tocris products. Selected citations for MJ 15 include:

2 Citations: Showing 1 - 2

  1. Cannabinoid WIN-55,212-2 mesylate inhibits tumor necrosis factor-α-induced expression of nitric oxide synthase in dorsal root ganglion neurons.
    Authors: Tan and Cao
    Int J Mol Med  2018;42:919
  2. Cannabinoid WIN-55,212-2 mesylate inhibits ADAMTS-4 activity in human osteoarthritic articular chondrocytes by inhibiting expression of syndecan-1.
    Authors: Kong Et al.
    J Virol  2016;13:4569

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