ML 184

Key Product Details

Product Description

ML 184 is a selective GPR55 agonist (EC₅₀ = 250 nM). Exhibits >100-fold selectivity for GPR55 over GPR35, CB₁ and CB₂. Increases proliferation of neural stem cells and promotes neuronal differentiation in vitro.

Product Specifications for ML 184

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for ML 184

The following data is based on the product molecular weight 470.63.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.2 mM	10.62 mL	53.12 mL	106.24 mL
1 mM	2.12 mL	10.62 mL	21.25 mL
2 mM	1.06 mL	5.31 mL	10.62 mL
10 mM	0.21 mL	1.06 mL	2.12 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Kotsikorou Identification of the GPR55 agonist binding site using a novel set of high-potency GPR55 selective ligands. Biochemistry 2011 PMID: 21534610
• Hill Activation of GPR55 increases neural stem cell proliferation and promotes early adult hippocampal neurogenesis. Br.J.Pharmacol. 2018 PMID: 29888782

Product Documents for ML 184