ML 298 hydrochloride
Chemical Name: 3,4-Difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]benzamide hydrochloride
Biological ActivitySelective inhibitor of phospholipase D2 (PLD2) (IC50 values are 355 and >20,000 nM for PLD2 and PLD1, respectively). Decreases invasive migration in U87-MG glioblastoma cells, without affecting cell viability.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Citation for ML 298 hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for ML 298 hydrochloride include:
1 Citation: Showing 1 - 1
Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors.
Authors: Hartlerode Et al.
Nat Struct Mol Biol 2015;22:736
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