ML 298 hydrochloride

Catalog # Availability Size / Price Qty
4895/10
4895/50
Cat.No. 4895 - ML 298 hydrochloride | C22H23F3N4O2.HCl
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Description: Selective PLD2 inhibitor

Chemical Name: 3,4-Difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]benzamide hydrochloride

Purity: ≥98%

Product Details
Citations (1)
Reviews

Biological Activity

Selective inhibitor of phospholipase D2 (PLD2) (IC50 values are 355 and >20,000 nM for PLD2 and PLD1, respectively). Decreases invasive migration in U87-MG glioblastoma cells, without affecting cell viability.

Technical Data

M.Wt:
468.9
Formula:
C22H23F3N4O2.HCl
Solubility:
Soluble to 25 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Product Datasheets

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Citation for ML 298 hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for ML 298 hydrochloride include:

1 Citation: Showing 1 - 1

  1. Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors.
    Authors: Hartlerode Et al.
    Nat Struct Mol Biol  2015;22:736

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