ML 348

  ( 1 citations )    
Product Datasheet
Catalog Number:5345
Chemical Name:N-[2-Chloro-5-(trifluoromethyl)phenyl]-4-(2-furanylcarbonyl)-1-piperazineacetamide
Product Details
Citations (1)
Reviews
Biological Activity
Selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM). Exhibits 14-fold selectivity for LYPLA1 over LYPLA2. Also selective over a panel of ~30 other serine hydrolases.
Technical Data
  • M.Wt:
    415.79
  • Formula:
    C18H17ClF3N3O3
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    899713-86-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for ML 348 include:

1 Citations: Showing 1 - 1

  1. Acyl protein thioesterase 1 and 2 (APT-1, APT-2) inhibitors palmostatin B, ML348 and ML349 have different effects on NRAS mutant melanoma cells.
    Authors: Vujic Et al.
    Oncotarget  2016;7:7297

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