Catalog Number: 5345
Chemical Name: N-[2-Chloro-5-(trifluoromethyl)phenyl]-4-(2-furanylcarbonyl)-1-piperazineacetamide
Biological Activity
Selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM). Exhibits 14-fold selectivity for LYPLA1 over LYPLA2. Also selective over a panel of ~30 other serine hydrolases.
Technical Data
  • M.Wt:
    415.79
  • Formula:
    C18H17ClF3N3O3
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Store at +4°C
  • CAS No:
    899713-86-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Characterization of a Selective, Reversible Inhibitor of Lysophospholipase 2 (LYPLA2).
    Adibekian et al.
    Probe Reports from the NIH Molecular Libraries Program, 2013;

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