Mouse Caspr2 (NP_001004357) VersaClone cDNA

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Mouse Caspr2 (NP_001004357) VersaClone cDNA
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Mouse Caspr2 (NP_001004357) VersaClone cDNA Summary


Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: Caspr2

Contactin-associated protein 2 (Caspr2) is a neuronal membrane protein and member of the neurexin family. Caspr2 is the mammalian homolog of Drosophila Neurexin IV. Caspr2 is believed to be involved in the local differentiation of the axon into distinct functional subdomains. Studies have shown that Caspr2 is essential for clustering of Shaker-type K+ channels in the juxtaparanodes of Ranvier. This effect is dependent on the association of Caspr2 with TAG-1, a glycosyl-phosphatidyl-inositol-anchored cell adhesion molecule. Mutations in Caspr2 are associated with the development of autism and related disorders.

Long Name
Contactin Associated Protein-like 2
Entrez Gene IDs
26047 (Human); 66797 (Mouse)
Alternate Names
AUTS15; Caspr2; CASPR2DKFZp781D1846; CDFE; Cell recognition molecule Caspr2; CNTNAP2; contactin associated protein-like 2; contactin-associated protein 2; contactin-associated protein-like 2; homolog of Drosophila neurexin IV; KIAA0868; NRXN4; NRXN4Caspr2; PTHSL1


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