Mouse CD161/NK1.1 APC‑conjugated Antibody

R&D Systems | Catalog # FAB8319A

R&D Systems
Discontinued Product
FAB8319A has been discontinued. View all CD161/NK1.1 products.

Key Product Details

Species Reactivity

Mouse

Applications

Flow Cytometry

Label

Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)

Antibody Source

Monoclonal Mouse IgG2A Clone # PK136
View all CD161/NK1.1 Primary Antibodies »

Product Specifications

Immunogen

Mouse NK-1+ splenocytes and bone marrow cells

Specificity

Detects mouse CD161/NK1.1 by flow cytometry

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for Mouse CD161/NK1.1 APC‑conjugated Antibody

Detection of CD161/NK1.1 antibody in C57BL/6 Mouse Splenocytes antibody by Flow Cytometry.

Detection of CD161/NK1.1 in C57BL/6 Mouse Splenocytes by Flow Cytometry.

C57BL/6 mouse splenocytes were stained with Rat Anti-Mouse NKp46/NCR1 PE-conjugated Monoclonal Antibody (Catalog # FAB22252P) and either (A) Mouse Anti-Mouse CD161/NK1.1 APC-conjugated Monoclonal Antibody (Catalog # FAB8319A) or (B) Mouse IgG2AAllophycocyanin Isotype Control (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins.

Applications for Mouse CD161/NK1.1 APC‑conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: C57BL/6 mouse splenocytes

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: CD161/NK1.1

CD161, also known as NK1.1, KLRB-1C, Ly-55, and NKR-P1c, is a 28 kDa type 2 transmembrane protein in the Killer Cell Lectin-like Receptor family. CD161 is expressed as a disulfide-linked homodimer on the surface of NK cells and subpopulations of NKT, CD4+, CD8+, and gamma / delta T cells. Its cross-linking on NK cells induces cytolytic activity, and on CD4 cells it promotes IgE production and the expansion of Th2 responses. Mature mouse CD161 consists of a 45 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 157 aa extracellular domain with one C-type lectin domain.

Alternate Names

Klrb1c, Ly-59, Ly55c

Entrez Gene IDs

17059 (Mouse)

Gene Symbol

KLRB1C

Additional CD161/NK1.1 Products

Product Documents for Mouse CD161/NK1.1 APC‑conjugated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Mouse CD161/NK1.1 APC‑conjugated Antibody

For research use only

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