CD177 is polymorphic and has at least two alleles, PRV1 and NB1. Human PRV1 is a 55-65 kDa, glycosyl-phosphotidylinositol (GPI) linked glycoprotein that belongs to the uPAR/CD59/Ly6 family of receptors. PRV1 is expressed by neutrophils and neutrophil precursors, and changes in expression serve as diagnostic markers for myeloproliferative disorders such as polycythemia vera and essential thrombocythemia. Erythroblasts, B cells, and monocytes may also express PRV1.
Mouse CD177 (NP_081138) VersaClone cDNA
R&D Systems | Catalog # RDC0593
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: CD177
Long Name
Polycythemia Rubra Vera Protein 1
Alternate Names
CD177, HNA-2a, NB1 GP, PRV1
Gene Symbol
CD177
UniProt
Additional CD177 Products
Product Documents for Mouse CD177 (NP_081138) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Mouse CD177 (NP_081138) VersaClone cDNA
For research use only
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