Mouse CD300b/LMIR5 (NP_954691.3) VersaClone cDNA

Name: Mouse CD300b/LMIR5 (NP_954691.3) VersaClone cDNA
Brand: R&D Systems
SKU: RDC3338
Price: 270 USD
Availability: InStock

R&D Systems | Catalog # RDC3338

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Product Documents

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Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species

Mouse

Accession Number

NP_954691.3

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: HLA-B

HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described. [provided by RefSeq]

Long Name

Major Histocompatibility Complex, Class I, B

Alternate Names

B-4901, HLAB

Entrez Gene IDs

3106 (Human)

Gene Symbol

HLA-B

UniProt

NP_954691.3

Additional HLA-B Products

Product Documents for Mouse CD300b/LMIR5 (NP_954691.3) VersaClone cDNA

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Certificate of Analysis

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Product Specific Notices for Mouse CD300b/LMIR5 (NP_954691.3) VersaClone cDNA

For research use only

Related Research Areas

Infectious Diseases

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