CMG-2 is an anthrax toxin receptor (ATR) family protein that contains one von Willebrand factor type A domain. As a result of alternative splicing, at least four isoforms of secreted or type I membrane proteins exist. CMG-2 is widely expressed in human tissues. It binds selectively to collagen type IV and laminin and is also capable of binding the protective antigen (PA) of Bacillus anthracis in a divalent cation-dependent manner. Soluble CMG-2 is a potent antitoxin and may be used as a treatment for anthrax.
Mouse CMG-2/ANTXR2 (NP_598499) VersaClone cDNA
R&D Systems | Catalog # RDC2529
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: CMG-2/ANTXR2
Long Name
Capillary Morphogenesis Protein 2
Alternate Names
ANTXR2, cI-35, CMG2, ISH, JHS
Gene Symbol
ANTXR2
UniProt
Additional CMG-2/ANTXR2 Products
Product Documents for Mouse CMG-2/ANTXR2 (NP_598499) VersaClone cDNA
Product Specific Notices for Mouse CMG-2/ANTXR2 (NP_598499) VersaClone cDNA
For research use only
Related Research Areas
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