Gas6 (Growth Arrest Specific 6) is a secreted protein that contains an extensively gamma-carboxylated N-terminal Gla domain and is dependent upon vitamin K for activity. Gas6 signals through the receptors Axl, Dtk/Tyro3, and Mer and is inhibited by shed soluble forms of Axl and Mer. Gas6 protects cells from stress-induced apoptosis and promotes phagocytosis of apoptotic cell debris, promotes platelet activation but inhibits inflammatory cytokine production, and inhibits VEGF-induced angiogenesis, and regulates tumor cell invasiveness.
Mouse Gas6 (CAA42507.1) VersaClone cDNA
R&D Systems | Catalog # RDC3753
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Gas6
Long Name
Growth-arrest-specific Protein 6
Alternate Names
AXLLG
Gene Symbol
GAS6
UniProt
Additional Gas6 Products
Product Documents for Mouse Gas6 (CAA42507.1) VersaClone cDNA
Product Specific Notices for Mouse Gas6 (CAA42507.1) VersaClone cDNA
For research use only
Related Research Areas
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