Mouse GPR20 (NP_775541) VersaClone cDNA

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R&D Systems VersaClone cDNA Plasmids
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Mouse GPR20 (NP_775541) VersaClone cDNA Summary


Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: GPR20

GPR20 is constitutively active in the absence of ligand, leading to continuous activation of its coupled G proteins. When GPR20 was exogenously expressed in HEK293 cells, both the basal level and the prostaglandin E(2)-induced production of cAMP were significantly decreased. Knockdown of GPR20 in PC12h cells resulted in an elevation of the basal cAMP level, suggesting that the endogenous GPR20 achieves a constitutively or spontaneously active conformation. GPR20 may be involved in cellular processes, including control of intracellular cAMP levels and mitogenic signaling.

Long Name
G Protein-coupled Receptor 20
Entrez Gene IDs
2843 (Human); 239530 (Mouse); 60667 (Rat)
Alternate Names
G protein-coupled receptor 20; GPR20; G-protein coupled receptor 20


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