Mouse IL‑16 Alexa Fluor® 700-conjugated Antibody

Catalog # Availability Size / Price Qty
AF1727N-100UG

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Mouse IL‑16 Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse IL-16 in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant human IL‑16 is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse IL-16
Ser1205-Ser1322
Accession # O54824
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: IL-16

Interleukin 16, also known as lymphocyte chemoattractant factor (LCF), refers to the C-terminal peptide of mouse pro-IL-16 or neuronal IL-16, which are nuclear and cytoplasmic PD2 domain containing proteins. The C-termini of these proteins are cleaved by Caspase-3, resulting in the release of secreted IL-16. Mature IL-16 has been shown to bind the cell surface receptor CD4 and function as an immunomodulatory cytokine. The C-terminal peptide of human and mouse IL-16 share approximately 86% amino acid sequence identity.

Long Name
Interleukin 16
Entrez Gene IDs
3603 (Human); 16170 (Mouse)
Alternate Names
FLJ16806; FLJ42735; FLJ44234; HsT19289; IL16; IL-16; interleukin 16 (lymphocyte chemoattractant factor); LCF; LCFprIL-16; lymphocyte chemoattractant factor; neuronal interleukin 16; NIL16; PRIL16; prointerleukin 16; pro-interleukin-16

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