IL-28 receptor alpha subunit, also named interferon-lambda R1, is a type I transmembrane glycoprotein that is cytokine receptor family 2 member 12 (CRF2-12). It pairs with the IL-10 receptor beta subunit (IL-10 R beta, CRF2-4) to form the IL-28 R. This receptor interacts with the interferon-like cytokines (type III interferons) IL-28A (IFN-lambda 2), IL-28B (IFN-lambda 3) and IL-29 (IFN-lambda 1). Signaling through IL-28 R alpha results in upregulated expression of MHC class I antigens and anti-viral, anti-proliferative and anti-tumor activity.
Mouse IL-28 R alpha/IFN-lambda R1 NP_777276 VersaClone cDNA
R&D Systems | Catalog # RDC1599
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: IL-28 R alpha/IFN-lambda R1
Long Name
Interleukin 28 Receptor alpha
Alternate Names
CRF2-12, IFN-lambda R1, IFNLR1, IL-28Ra, IL28R alpha, IL28RA, LICR2
Gene Symbol
IFNLR1
UniProt
Additional IL-28 R alpha/IFN-lambda R1 Products
Product Documents for Mouse IL-28 R alpha/IFN-lambda R1 NP_777276 VersaClone cDNA
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Product Specific Notices for Mouse IL-28 R alpha/IFN-lambda R1 NP_777276 VersaClone cDNA
For research use only
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