Mouse Lymphotoxin  beta R/TNFRSF3 PE-conjugated Antibody

FAB10081P has been discontinued. View all Lymphotoxin beta R/TNFRSF3 products.
    
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  • Species Reactivity
    Mouse
  • Specificity
    Detects mouse Lymphotoxin beta R in direct ELISAs and Western blots. In direct ELISAs, does not cross-react with recombinant mouse (rm) 4‑1BB, rmBAFF R, rmCD27, rmCD30, rmCD40, recombinant human (rh) DR3, rhDR6, rmEDAR, rmFas, rmGITR, rmHVEM, rhLymphotoxin  beta R, rmNGF R, rmOPG, rmOX40, rmRANK, rhRELT, rmTAJ, rmTNF RI, rmTNF RII, rhTRADD, rmTRAIL R2, rhTRAIL R3, rhTRAIL R4, or rmTWEAK R.
  • Source
    Monoclonal Rat IgG2A Clone # 157108
  • Purification
    Protein A or G purified from hybridoma culture supernatant
  • Immunogen
    Mouse myeloma cell line NS0-derived recombinant mouse Lymphotoxin beta R/TNFRSF3
    Ser28-Pro218
    Accession # P50284
  • Formulation
    Supplied in a saline solution containing BSA and Sodium Azide.
  • Label
    Phycoerythrin
Product Datasheets

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Applications
  •  
    Recommended
    Concentration
    Sample
  • Flow Cytometry
    10 µL/106 cells
    See below
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Example
Detection of Lymphotoxin  beta R/TNFRSF3 in NIH‑3T3 Mouse Cell Line by Flow Cytometry. NIH‑3T3 mouse embryonic fibroblast cell line was stained with Rat Anti-Mouse Lymphotoxin  beta R/TNFRSF3 PE‑conjugated Monoclonal Antibody (Catalog # FAB10081P, filled histogram) or isotype control antibody (Catalog # IC006P, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
  • Shipping
    The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    Protect from light. Do not freeze.
    • 12 months from date of receipt, 2 to 8 °C as supplied.
Background: Lymphotoxin beta R/TNFRSF3
Lymphotoxin beta R, now designated TNFRSF3, is a cell surface protein expressed in a variety of tissues. Lymphotoxin beta R transduces signals following binding of LIGHT or the heterotrimeric lymphotoxin LT alpha 1/ beta 2 or LT alpha 2/ beta 1. It plays a critical role in controlling cellular immune functions and lymphoid organogenesis.
  • Long Name:
    Lymphotoxin beta Receptor
  • Entrez Gene IDs:
    4055 (Human); 17000 (Mouse); 297604 (Rat)
  • Alternate Names:
    CD18; D12S370; ltbetar; LT-BETA-R; LTBR; lymphotoxin B receptor; Lymphotoxin beta R; lymphotoxin beta receptor (TNFR superfamily, member 3); Lymphotoxin-beta receptor; LymphotoxinbR; TNF RIII; TNF Rrp; TNFCRTNF-RIII; TNFR superfamily, member 3; TNFR2-RP; TNFR3; TNF-R-III; TNFR-RP; TNFRSF3; TNFRSF3TNFR-III; Tumor necrosis factor C receptor; Tumor necrosis factor receptor 2-related protein; tumor necrosis factor receptor superfamily member 3; tumor necrosis factor receptor superfamily, member 3; Tumor necrosis factor receptor type III
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