Mouse MDR1/ABCB1B (NP_035205) VersaClone cDNA

Name: Mouse MDR1/ABCB1B (NP_035205) VersaClone cDNA
Brand: R&D Systems
SKU: RDC0756
Price: 1079 USD
Availability: InStock

R&D Systems | Catalog # RDC0756

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Background
Product Documents
Specific Notices

Key Product Details

Species

Mouse

Accession Number

NP_035205

Background: MDR1/ABCB1

MDR1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). MDR1 is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. (provided by RefSeq)

Long Name

ATP-binding Cassette, Sub-family B (MDR/TAP), Member 1B

Alternate Names

ABC20, ABCB1, ABCB1B, CD243, CLCS, GP170, IBD13, PGY1

Entrez Gene IDs

5243 (Human); 18669 (Mouse); 24646 (Rat)

Gene Symbol

ABCB1

UniProt

NP_035205

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Product Specific Notices for Mouse MDR1/ABCB1B (NP_035205) VersaClone cDNA

For research use only

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