OCIL/CLEC2D, also known as lectin-like transcript-1 (LLT-1), is a type II transmembrane protein belonging to the natural killer cell receptor group of the C-type lectin superfamily. It is found on hematopoietic cells, osteoblasts, and chondrocytes. Human OCIL preferentially binds high molecular weight sulfated glycosaminoglycans and is a ligand for the single human NKR-P1A receptor (CD161). Human OCIL blocks osteoclast differentiation. Engagement of OCIL with CD161 on NK cells also inhibits NK cell-mediated cytotoxicity and IFN-gamma secretion.
Mouse OCIL/CLEC2d (NP_444339) VersaClone cDNA
R&D Systems | Catalog # RDC2548
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: OCIL/CLEC2d
Long Name
Osteoclast Inhibitory Lectin
Alternate Names
CLEC2D, LLT1
Gene Symbol
CLEC2D
UniProt
Additional OCIL/CLEC2d Products
Product Documents for Mouse OCIL/CLEC2d (NP_444339) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Mouse OCIL/CLEC2d (NP_444339) VersaClone cDNA
For research use only
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