Mouse TMEFF1/Tomoregulin-1 (NP_001343201.1) VersaClone cDNA

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Mouse TMEFF1/Tomoregulin-1 (NP_001343201.1) VersaClone cDNA
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Mouse TMEFF1/Tomoregulin-1 (NP_001343201.1) VersaClone cDNA Summary


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Background: TMEFF1/Tomoregulin-1

Transmembrane Protein with EGF-like and two Follistatin-like domains 1 (TMEFF1) also known as tomoregulin-1 is a type I transmembrane glycoprotein. TMEFF1 contains two follistatin modules and an EGF domain in its extracellular domain, a transmembrane domain and a short cytoplasmic tail. The extracellular domain of TMEFF1 can be released as a soluble protein. TMEFF1 is predominantly expressed in brain, but is downregulated in brain neoplasms. TMEFF1 selectively regulates nodal but not activin signaling through direct binding to the nodal co-receptor, Cripto.

Long Name
Transmembrane Protein with EFG-like and two Follistatin-like Domains
Entrez Gene IDs
8577 (Human); 230157 (Mouse)
Alternate Names
C9orf2; H7365member 1; TMEFF1; Tomoregulin1; Tomoregulin-1; TR-1; Transmembrane protein with EGF-like and one follistatin-like domain; transmembrane protein with EGF-like and two follistatin-like domains 1


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