TSPAN1 belongs to the large family of tetraspanins, so named because they contain 4 transmembrane domains. TSPAN1 is expressed in colon, endometrium, pancreas, normal and neoplastic prostate, and pregnant uterus. Tetraspanins are frequently expressed at the cell surface in association with each other and with other molecules, such as integrins, and they function to regulate cell adhesion, migration, proliferation, and differentiation. RNAi-mediated downregulation of TSPAN1 expression significantly inhibits the proliferation and invasion of colon cancer cells in vitro. This finding suggests that TSPAN1 plays an important role in colon cancer progression.
Mouse TSPAN1 (NP_598442) VersaClone cDNA
R&D Systems | Catalog # RDC2612
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: TSPAN1
Long Name
Tetraspanin 1
Alternate Names
NET1, TM4C, TM4SF
Gene Symbol
TSPAN1
UniProt
Additional TSPAN1 Products
Product Documents for Mouse TSPAN1 (NP_598442) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Mouse TSPAN1 (NP_598442) VersaClone cDNA
For research use only
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