MRS 2211

  ( 9 citations )    
Product Datasheet
Catalog Number:2402
Chemical Name:2-[(2-Chloro-5-nitrophenyl)azo]-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]-4-pyridinecarboxaldehyde disodium salt
Product Details
Citations (9)
Supplemental Products
Reviews
Biological Activity
Competitive P2Y13 receptor antagonist (pIC50 = 5.97) that displays > 20-fold selectivity over P2Y1 and P2Y12 receptors.
Technical Data
  • M.Wt:
    474.66
  • Formula:
    C14H10N4O8Na2PCl
  • Solubility:
    Soluble to 70 mM in water
  • Purity:
    >96
  • Storage:
    Desiccate at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for MRS 2211 include:

9 Citations: Showing 1 - 9
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  1. Autocrine Regulation of UVA-Induced IL-6 Production via Release of ATP and Activation of P2Y Receptors.
    Authors: Kawano Et al.
    PLoS One  2015;10:e0127919
  2. Anti-platelet therapy with clopidogrel prevents endothelial dysfunction and vascular remodeling in aortas from hypertensive rats.
    Authors: Giachini Et al.
    PLoS One  2014;9:e91890
  3. Nucleolin down-regulation is involved in ADP-induced cell cycle arrest in S phase and cell apoptosis in vascular endothelial cells.
    Authors: Wang Et al.
    PLoS One  2014;9:e110101
  4. The enteric nervous system of P2Y13 receptor null mice is resistant against high-fat-diet- and palmitic-acid-induced neuronal loss.
    Authors: Voss Et al.
    Purinergic Signal  2014;10:455
  5. The role of P2Y(14) and other P2Y receptors in degranulation of human LAD2 mast cells.
    Authors: Gao Et al.
    Mol Cancer  2013;9:31
  6. Bradykinin-induced Ca2+ signaling in human subcutaneous fibroblasts involves ATP release via hemichannels leading to P2Y12 receptors activation.
    Authors: Pinheiro Et al.
    Cell Commun Signal  2013;11:70
  7. Constitutively released adenosine diphosphate regulates proplatelet formation by human megakaryocytes.
    Authors: Balduini Et al.
    Haematologica  2012;97:1657
  8. Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation.
    Authors: Puerto Et al.
    J Cell Sci  2012;125:176
  9. Increase of intracellular Ca2+ by purinergic receptors in cultured rat lacrimal gland myoepithelial cells.
    Authors: Ohtomo Et al.
    Invest Ophthalmol Vis Sci  2011;52:9503

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