Home / GPR171 Antagonists / MS 21570

MS 21570

Catalog #: 6298 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6298/50
6298/10
MS 21570 | CAS No. 65373-29-7 | GPR171 Antagonists
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Description: GPR171 antagonist

Chemical Name: N-Methyl-5-[(phenylmethyl)thio]-1,3,4-thiazadiazol-2-amine

Purity: ≥98%

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Biological Activity

MS 21570 is a GPR171 antagonist (IC50 = 220 nM). Inhibits BigLEN (Cat.No. 6304) mediated increases in [35S]GTPγS binding in hypothalamic membranes and hyperpolarization of basolateral amygdala pyramidal neurons. Reduces anxiety-like behavior and fear conditioning in mice.

Technical Data

M.Wt:
237.34
Formula:
C10H11N3S2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
65373-29-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Complete Your Experiment

MS 15203
Cat # 6299

Product Datasheets

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FAQs

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VersaClone cDNA Plasmids

Human GPR171 (NP_037440) VersaClone cDNA

RDC0758

Mouse GPR171 (NP_775574) VersaClone cDNA

RDC0759

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