MST1/2 Antibody

Novus Biologicals | Catalog # NBP1-28672

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Equine (100%), Guinea Pig (100%), Monkey (100%), Mouse (100%), Orangutan (100%), Rabbit (100%), Rat (100%), Turkey (100%), Xenopus (100%), Zebrafish (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all MST1/2 Primary Antibodies »

Product Specifications

Immunogen

The immunogen this antibody was made to, maps to the C-terminus of human Mammalian Sterile 20-like 2 (Serine/Threonine Kinase 3) using the numbering given in Swiss Prot entry Q13188 (GeneID 6788). The epitope is highly conserved with MST1(STK4).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MST1/2 Antibody

Immunohistochemistry-Paraffin: MST1/2 Antibody [NBP1-28672]

Immunohistochemistry-Paraffin: MST1/2 Antibody [NBP1-28672]

Immunohistochemistry-Paraffin: MST1/2 Antibody [NBP1-28672] - Section of human colon carcinoma. Antibody: Affinity purified rabbit antiMST1,2/STK3,4 used at a dilution of 1:250. Detection: DAB
Immunohistochemistry-Paraffin: MST1/2 Antibody [NBP1-28672]

Immunohistochemistry-Paraffin: MST1/2 Antibody [NBP1-28672]

Immunohistochemistry-Paraffin: MST1/2 Antibody [NBP1-28672] - Section of human placenta. Antibody: Affinity purified rabbit antiMST1,2/STK3,4 used at a dilution of 1:250. Detection: DAB

Applications for MST1/2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100 - 1:500

Immunohistochemistry-Paraffin

1:100-1:500
Application Notes
Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.25 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: MST1/2

MST1 and MST2 are members of the sterile 20 (Ste20)-like kinase family that acts upstream of mitogen-activated protein kinase (MAPK) pathways and regulates c-Jun N-terminal kinase (JNK), p38 and extracellular signal-regulated kinase (ERK). Ste20-like kinases are involved in a variety of cellular processes which include gene transcription, stress responses, cytoskeletal organization and apoptosis. In response to apoptotic signals, MST1 and MST2 are cleaved by caspase-3 and mediate apoptosis.

Alternate Names

KRS1, KRS2, Mammalian STE20-like protein kinase 1, Mammalian STE20-like protein kinase 2, mammalian sterile 20-like 1, serine/threonine-protein kinase 3, serine/threonine-protein kinase 4, Serine/threonine-protein kinase Krs-1, YSK3

Entrez Gene IDs

6788 (Human)

Gene Symbol

STK3

UniProt

Q13188

Additional MST1/2 Products

Product Documents for MST1/2 Antibody

Certificate of Analysis

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Product Specific Notices for MST1/2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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