Myosin Light Chain 2 Antibody (RM484)

Novus Biologicals | Catalog # NBP3-18830

Recombinant Monoclonal Antibody
Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # RM484 expressed in HEK293
View all Myosin Light Chain 2 Primary Antibodies »

Product Specifications

Immunogen

A phospho-peptide corresponding to human Myosin Light Chain 2 [Ser19]

Specificity

This antibody reacts to Myosin Light Chain 2 only when phosphorylated at Ser19. There is no cross-reactivity to Myosin Light Chain 2 that is not phosphorylated.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Myosin Light Chain 2 Antibody (RM484)

Myosin Light Chain 2 Antibody (RM484)

Western Blot: Myosin Light Chain 2 Antibody (RM484)[NBP3-18830]

Western Blot: Myosin Light Chain 2 Antibody (RM484)[NBP3-18830]Western Blot of mouse heart tissue lysate, using Anti-Phospho-Myl2 (Ser19) rabbit monoclonal antibody (clone RM484) at a 1:1000 dilution. The phospho-specificity of RM484 was verified by peptide blocking using a control non-phosphopeptide or phosphopeptide targeting residue Ser19.

Applications for Myosin Light Chain 2 Antibody (RM484)

Application
Recommended Usage

Western Blot

1:1000-1:2000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50% Glycerol/PBS, 1% BSA

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C.

Background: Myosin Light Chain 2

MYL2 (myosin, light chain 2, regulatory, cardiac, slow), also known as MLC-2, MLC2v. Entrez protein NP_000423. MYL2 associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. It is an hexamer of two heavy chains and four light chains that is predominantly expressed in adult cardiac ventricle muscle. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.

Alternate Names

cardiac ventricular myosin light chain 2, CMH10myosin light chain 2, DKFZp779C0562, MLC2, MLC-2, MLC-2v, myosin regulatory light chain 2, ventricular/cardiac muscle isoform, myosin, light chain 2, regulatory, cardiac, slow, myosin, light polypeptide 2, regulatory, cardiac, slow, regulatory light chain of myosin, RLC of myosin, slow cardiac myosin regulatory light chain 2

Gene Symbol

MYL2

Additional Myosin Light Chain 2 Products

Product Documents for Myosin Light Chain 2 Antibody (RM484)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Myosin Light Chain 2 Antibody (RM484)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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