N-methylated pomalidomide

Tocris Bioscience | Catalog # 7716

Functionalized cereblon ligand for generating Degrader negative controls; also used as Pomalidomide negative control
Tocris Bioscience

Key Product Details

Description

Functionalized cereblon ligand for generating Degrader negative controls; also used as Pomalidomide negative control
View all Active Degrader Negative Controls »

Product Description

N-methylated pomalidomide is a functionalized cereblon ligand for PROTAC® research and development. Can be used to generate negative controls for Pomalidomide (Cat. No. 6302)-based Degraders. Does not bind to cereblon. Part of a range of functionalized tool molecules for PROTAC R&D. Can also be used as a Pomalidomide negative control.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Product Specifications for N-methylated pomalidomide

Molecular Weight

287.27

Formula

C14H13N3O4

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

4-Amino-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione

CAS Number

1352827-50-9

PubChem ID

58572149

InChI Key

YSWQOCGODHPKED-UHFFFAOYSA-N

SMILES

O=C1C=2C=CC=C(N)C2C(=O)N1C3C(=O)N(C(=O)CC3)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 28.73 100

Preparing Stock Solutions for N-methylated pomalidomide

The following data is based on the product molecular weight 287.27.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.48 mL 17.41 mL 34.81 mL
5 mM 0.70 mL 3.48 mL 6.96 mL
10 mM 0.35 mL 1.74 mL 3.48 mL
50 mM 0.07 mL 0.35 mL 0.70 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

There are currently no references for this product.

Product Documents for N-methylated pomalidomide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for N-methylated pomalidomide

For research use only

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