Catalog Number: 1702
Alternate Names: CPA
Chemical Name: N-Cyclopentyladenosine
Biological Activity
Potent and selective adenosine A1 receptor agonist (Ki values are 2.3, 790 and 43 nM for human A1, A2A and A3 receptors respectively; EC50 = 18600 nM for hA2B). Centrally active following systemic administration in vivo.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in 1eq. HCl
  • Purity:
  • Storage:
    Desiccate at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Adenosine receptors and their ligands.
    Naunyn Schmiedebergs Arch.Pharmacol., 2000;362:382
  2. Behavioral and cardiovascular effects of analogs of adenosine in Cynomolgus monkeys.
    Coffin and Spealman
    J.Pharmacol.Exp.Ther., 1987;241:76
  3. Mechanism-based pharmacokinetic-pharmacodynamic modeling of the effects of N6-cyclopentyladenosine analogs on heart rate in rat: estimation of in vivo operational affinity and efficacy at adenosine A1 receptors.
    Van der Graaf et al.
    J.Pharmacol.Exp.Ther., 1997;283:809
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