N6-Cyclopentyladenosine

  ( 12 citations )    
Product Datasheet
Catalog Number:1702
Alternate Names:CPA
Chemical Name:N-Cyclopentyladenosine
Product Details
Citations (12)
Supplemental Products
Reviews
Biological Activity
Potent and selective adenosine A1 receptor agonist (Ki values are 2.3, 790 and 43 nM for human A1, A2A and A3 receptors respectively; EC50 = 18600 nM for hA2B). Centrally active following systemic administration in vivo.
Technical Data
  • M.Wt:
    335.36
  • Formula:
    C15H21N5O4
  • Solubility:
    Soluble to 100 mM in 1eq. HCl
  • Purity:
    >99
  • Storage:
    Desiccate at +4°C
  • CAS No:
    41552-82-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for N6-Cyclopentyladenosine include:

12 Citations: Showing 1 - 10
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  1. Adenosine arrests breast cancer cell motility by A3 receptor stimulation.
    Authors: Ledderose Et al.
    Purinergic Signalling  2016;
  2. Role of adenosine receptor subtypes in methamphetamine reward and reinforcement.
    Authors: Kavanagh Et al.
    PLoS One  2015;89:265
  3. Characterization of spontaneous, transient adenosine release in the caudate-putamen and prefrontal cortex.
    Authors: Nguyen Et al.
    PLoS One  2014;9:e87165
  4. Cancellation of cellular responses to nanoelectroporation by reversing the stimulus polarity.
    Authors: Pakhomov Et al.
    Cell Mol Life Sci  2014;71:4431
  5. Characterization by flow cytometry of fluorescent, selective agonist probes of the A(3) adenosine receptor.
    Authors: Kozma Et al.
    Biochem Pharmacol  2013;85:1171
  6. Lysosomes shape Ins(1,4,5)P3-evoked Ca2+ signals by selectively sequestering Ca2+ released from the endoplasmic reticulum.
    Authors: López-Sanjurjo Et al.
    J Cell Sci  2013;126:289
  7. Stimulation of adenosine receptors in the nucleus accumbens reverses the expression of cocaine sensitization and cross-sensitization to dopamine D2 receptors in rats.
    Authors: Hobson Et al.
    Neuropharmacology  2012;63:1172
  8. Translocation of CaMKII to dendritic microtubules supports the plasticity of local synapses.
    Authors: Lemieux Et al.
    J Cell Biol  2012;198:1055
  9. Regulation of hippocampal cannabinoid CB1 receptor actions by adenosine A1 receptors and chronic caffeine administration: implications for the effects of δ9-tetrahydrocannabinol on spatial memory.
    Authors: Sousa Et al.
    Neuropsychopharmacology  2011;36:472
  10. Presynaptically expressed long-term potentiation increases multivesicular release at parallel fiber synapses.
    Authors: Bender Et al.
    J Neurosci  2009;29:10974
  11. Presynaptic plasma membrane Ca2+ ATPase isoform 2a regulates excitatory synaptic transmission in rat hippocampal CA3.
    Authors: Jensen Et al.
    Neuropharmacology  2007;579:85
  12. Contribution of both Ca2+ entry and Ca2+ sensitization to the alpha1-adrenergic vasoconstriction of rat penile small arteries.
    Authors: Villalba Et al.
    Am J Physiol Heart Circ Physiol  2007;292:H1157
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