Potent and selective adenosine A1
receptor agonist (Ki
values are 2.3, 790 and 43 nM for human A1
receptors respectively; EC50
= 18600 nM for hA2B
). Centrally active following systemic administration in vivo
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Adenosine receptors and their ligands.
Naunyn Schmiedebergs Arch.Pharmacol., 2000;362:382
Behavioral and cardiovascular effects of analogs of adenosine in Cynomolgus monkeys.
Coffin and Spealman
Mechanism-based pharmacokinetic-pharmacodynamic modeling of the effects of N6-cyclopentyladenosine analogs on heart rate in rat: estimation of in vivo operational affinity and efficacy at adenosine A1 receptors.
Van der Graaf et al.
The citations listed below are publications that use Tocris products. Selected citations for N6-Cyclopentyladenosine include:
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