Catalog Number: 4085
Chemical Name: (5α)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinan-3,14-diol hydrochloride
Biological Activity
Opioid receptor antagonist; displays a longer half life than Naloxone (Cat. No. 0599). Exhibits neuroprotective effects after traumatic brain injury in the rat. Deuterated version, Nalmefene d3 (Cat. No. 3971), also available.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Purity:
  • Storage:
    Desiccate at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. Opiate antagonist nalmefene improves intracellular free Mg2+, bioenergetic state, and neurologic outcome following traumatic brain injury in rats.
    Vink et al.
    J.Neurosci., 1990;10:3524
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