Naloxone hydrochloride

Key Product Details

Product Description

Naloxone hydrochloride is an opioid antagonist.

Product Specifications for Naloxone hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Naloxone hydrochloride

The following data is based on the product molecular weight 363.84.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.75 mL	13.74 mL	27.48 mL
5 mM	0.55 mL	2.75 mL	5.50 mL
10 mM	0.27 mL	1.37 mL	2.75 mL
50 mM	0.05 mL	0.27 mL	0.55 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 120 publications citing the usage of this product.

• Spivak Naloxone activation of mu-opioid receptors mutated at a histidine residue lining the opioid cavity. Mol.Pharmacol. 1997 PMID: 9415708
• Olson Endogenous opiates: 1995. Peptides
• Pinelli and Trivulzio Quantitative evaluation of opioid withdrawal signs in rats repeatedly treated with mor. and injected with naloxone, in the absence or presence of the antiabstinence agent clon. J.Pharmacol.Toxicol.Methods 1997 PMID: 9523765

Product Documents for Naloxone hydrochloride