NDM-1 Antibody [FITC]

Novus Biologicals | Catalog # NBP1-77688F

Novus Biologicals
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Key Product Details

Species Reactivity

Mouse, Bacteria, E. coli

Applications

Western Blot

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Polyclonal Rabbit IgG
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Product Specifications

Immunogen

A synthetic peptide made to a C-terminal region of the E. coli bla-NDM-1 protein (within residues 100-158). [NCBI BAJ10873]

Reactivity Notes

E. coli reactivity reported in scientific literature (PMID: 30323356). Use in Mouse reported in scientific literature (PMID:32014252).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for NDM-1 Antibody [FITC]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This NDM1 antibody is useful for Western blot where a band is seen ~12 kDa in recombinant protein. Note: This enzyme may form multimers.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: NDM-1

New Delhi metallo-beta-lactamase is an enzyme that predisposes bacteria to become antibiotic resistant. In Pakistan, multi-drug resistant bacteria are blamed for a higher than usual incidence of hospital infections. NDM1 has an interesting conformational design, in that it has a large active site which allows it to react with multiple substrates, and which changes distinctly after substrates bind to it. Therapies against NDM1 in tandem with antibiotic therapies are being postulated as the best potential defense against antibiotic resistance. However, the ability to identify NDM1 prevalence is also critical. Identification of colonized individuals by immunodetection assays could be a critical step in isolation and treatment.

Additional NDM-1 Products

Product Documents for NDM-1 Antibody [FITC]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for NDM-1 Antibody [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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