Nectin-2/CD112 Antibody (610615) [DyLight 488]

Name: Nectin-2/CD112 Antibody (610615) [DyLight 488]
Brand: Novus Biologicals
SKU: FAB22291K
Price: 539 USD
Availability: InStock

Novus Biologicals | Catalog # FAB22291K

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Neutralization

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Monoclonal Mouse IgG_2B Clone # 610615

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Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Nectin-2/CD112
Gln32-Gly360
Accession # Q92692

Specificity

Detects human Nectin-2/CD112 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) Nectin-1, rhCD155/PVR, or recombinant mouse Nectin-2/CD112 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2B

Applications for Nectin-2/CD112 Antibody (610615) [DyLight 488]

Application

Recommended Usage

Neutralization

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Nectin-2/CD112

Nectin 2 encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Long Name

Poliovirus Receptor Related 2

Alternate Names

CD112, HVEB, MPH, Nectin2, PRR2, PVRL2

Additional Nectin-2/CD112 Products

Product Documents for Nectin-2/CD112 Antibody (610615) [DyLight 488]

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Certificate of Analysis

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Product Specific Notices for Nectin-2/CD112 Antibody (610615) [DyLight 488]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.