Recombinant Human Neurogenin-3 His Protein

Novus Biologicals | Catalog # NBP2-51514

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE
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Product Specifications

Description

A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-214 of Human Neurogenin-3

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MTPQPSGAPT VQVTRETERS FPRASEDEVT CPTSAPPSPT RTRGNCAEAE EGGCRGAPRK LRARRGGRSR PKSELALSKQ RRSRRKKAND RERNRMHNLN SALDALRGVL PTFPDDAKLT KIETLRFAHN YIWALTQTLR IADHSLYALE PPAPHCGELG SPGGSPGDWG SLYSPVSQAG SLSPAASLEE RPGLLGATSS ACLSPGSLAF SDFL

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

25.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Application Notes

Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human Neurogenin-3 His Protein

SDS-PAGE: Recombinant Human Neurogenin-3 His Protein [NBP2-51514]

SDS-PAGE: Recombinant Human Neurogenin-3 His Protein [NBP2-51514]

SDS-Page: Recombinant Human Neurogenin-3 Protein [NBP2-51514] - 15% SDS Page (3 ug)

Formulation, Preparation, and Storage

NBP2-51514
Formulation 20 mM Tris-HCl buffer (pH 8.0), 10% glycerol, 0.4M UREA
Preservative No Preservative
Concentration 0.25 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Neurogenin-3

Neurogenin-3 (NEUROG3) is expressed in endocrine progenitor cells and is required for endocrine cell development in the pancreas and intestine (Wang et al., 2006 [PubMed 16855267]). It belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm (Gradwohl et al., 2000 [PubMed 10677506]).[supplied by OMIM]

Alternate Names

Atoh5, Math4B, NEUROG3, Neurogenin3, Relax

Gene Symbol

NEUROG3

Additional Neurogenin-3 Products

Product Documents for Recombinant Human Neurogenin-3 His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human Neurogenin-3 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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