Catalog Number: 1582
Alternate Names: NKB
Biological Activity
Endogenous tachykinin agonist peptide that shows preference for the NK3 receptor (EC50 = 1 nM).
Technical Data
  • M.Wt:
    1210.43
  • Formula:
    C55H79N13O14S2
  • Sequence:
    DMHDFFVGLM

    (Modifications: Met-10 = C-terminal amide)

  • Solubility:
    Soluble to 0.80 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    86933-75-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Neurokinin B is a preferred agonist for a neuronal substance P receptor and its action is antagonized by enkephalin.
    Laufer et al.
    Proc.Natl.Acad.Sci.U.S.A., 1985;82:7444
  2. The tachykinin peptide family.
    Severini et al.
    Pharmacol.Rev., 2002;54:285
  3. Neurokinin B potentiates ATP-activated currents in rat DRG neurons.
    Wang et al.
    Brain Res., 2001;923:157

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