Mouse NK3R/TACR3 (NP_067357) VersaClone cDNA

Name: Mouse NK3R/TACR3 (NP_067357) VersaClone cDNA
Brand: R&D Systems
SKU: RDC1078
Price: 270 USD
Availability: InStock

R&D Systems | Catalog # RDC1078

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Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species

Mouse

Accession Number

NP_067357

Background: NK3R/TACR3

The Neurokinins, also known as Tachykinins, belong to an evolutionary conserved family of peptide neurotransmitters that share a c-terminal sequence and have an established role in neurotransmission. The mammalian tachykinins include substance P (NK1), neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.

Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).

Long Name

Neurokinin-3 Receptor

Alternate Names

Neurokinin B Receptor, Neuromedin-K Receptor, TAC3RL, TACR3

Entrez Gene IDs

6870 (Human); 21338 (Mouse); 24808 (Rat)

Gene Symbol

TACR3

UniProt

NP_067357

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Product Specific Notices for Mouse NK3R/TACR3 (NP_067357) VersaClone cDNA

For research use only

Related Research Areas

Neurotransmitter G Protein-Coupled Receptors

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