Catalog Number: 1928
Alternate Names: NPAF, Neuropeptide NPAF (human FMRFamide-related)
Biological Activity
Endogenous antiopioid peptide, implicated in pain modulation and endocrine functions. May also regulate metabolism via stimulation of β-adrenoceptor expression in adipocytes.
Technical Data
  • M.Wt:
    1978.19
  • Formula:
    C90H132N26O25
  • Sequence:
    AGEGLNSQFWSLAAPQRF

    (Modifications: Phe-18 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    192387-38-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor.
    Elshourbagy et al.
    J.Biol.Chem., 2000;275:25965
  2. Neuropeptide AF and FF modulation of adipocyte metabolism.
    Lefrere et al.
    J.Biol.Chem., 2002;277:39169
  3. Gene for pain modulatory neuropeptide FF: induction in spinal cord by noxious stimuli.
    Vilim et al.
    Mol.Pharmacol., 1999;55:804

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