Endogenous antiopioid peptide and agonist at NPFF1
values are 2.82 and 0.21 nM respectively). Exhibits anorexigenic effects following i.c.v. administration.
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Central neuropeptide FF reduces feed consumption and affects hypothalamic chemistry in chicks.
Cline et al.
Functional differences between NPFF1 and NPFF2 receptor coupling: high intrinsic activities of RFamide-related peptides on stimulation of[35S]GTPγS binding.
Gouarderes et al.