Catalog Number: 3137
Biological Activity
Endogenous antiopioid peptide and agonist at NPFF1 and NPFF2 receptors (Ki values are 2.82 and 0.21 nM respectively). Exhibits anorexigenic effects following i.c.v. administration.
Technical Data
  • M.Wt:
    1081.28
  • Formula:
    C54H76N14O10
  • Sequence:
    FLFQPQRF

    (Modifications: Phe-8 = C-terminal amide)

  • Solubility:
    Soluble to 0.50 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    99566-27-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Central neuropeptide FF reduces feed consumption and affects hypothalamic chemistry in chicks.
    Cline et al.
    Neuropeptides, 2007;41:433
  2. Functional differences between NPFF1 and NPFF2 receptor coupling: high intrinsic activities of RFamide-related peptides on stimulation of[35S]GTPγS binding.
    Gouarderes et al.
    Neuropharmacology, 2007;52:376

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