Chemical Name: N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide
Biological ActivitySelective, orally active cyclooxygenase-2 (COX-2) inhibitor. Produces potent analgesic, anti-inflammatory and antipyretic activities in vivo. Reported to produce fewer gastrointestinal side effects than standard NSAIDs. .
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
In vitro and in vivo pharmacological evidence of selective cyclooxygenase-2 inhibition by nimesulide: an overview.
Selective cyclooxygenase-2 inhibition by nimesulide in man.
Cullen et al.
Citations for Nimesulide
The citations listed below are publications that use Tocris products. Selected citations for Nimesulide include:
3 Citations: Showing 1 - 3
Mechanisms of endothelium-dependent relaxation evoked by anandamide in isolated human pulmonary arteries.
Authors: Baranowska-Kuczko Et al.
J Neuroimmune Pharmacol 2014;387:477
MDMA increases glutamate release and reduces parvalbumin-positive GABAergic cells in the dorsal hippocampus of the rat: role of cyclooxygenase.
Authors: Anneken Et al.
Nat Commun 2013;8:58
Effects of COX-2 inhibition on spinal nociception: the role of endocannabinoids.
Authors: Staniaszek Et al.
Br J Pharmacol 2010;160:669
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