[Nle4,D-Phe7]-α-MSH

Tocris Bioscience | Catalog # 3013

Melanocortin receptor agonist
Tocris Bioscience

Key Product Details

Description

Melanocortin receptor agonist

Alternative Names

Melanotan I,MT-I,NDP-α-MSH
View all Melanocortin Receptor Agonists »

Product Description

[Nle4,D-Phe7]-α-MSH is a synthetic analog of α-MSH that is an agonist at melanocortin receptors (Ki values are 0.085, 0.4, 3.8 and 5.1 nM for MC1, MC3, MC4 and MC5 receptors respectively).

Product Specifications for [Nle4,D-Phe7]-α-MSH

Molecular Weight

1646.86

Formula

C78H111N21O19

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

75921-69-6

PubChem ID

16132139

InChI Key

UAHFGYDRQSXQEB-PWPYQVNISA-N

SMILES

CCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 0.6mg/ml in water

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 7 publications citing the usage of this product.

  • Sawyer 4-Norleucine, 7-D-phenylalanine-α-melanocyte-stimulating hormone: a highly potent α-melanotropin with ultrapotent biological activity. Proc.Natl.Acad.Sci.USA
  • Wikber Melanocortin receptors: perspectives for novel drugs. Eur.J.Pharmacol. 1999 PMID: 10443584

Product Documents for [Nle4,D-Phe7]-α-MSH

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for [Nle4,D-Phe7]-α-MSH

For research use only

Citations for [Nle4,D-Phe7]-α-MSH

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