NLRP10/Pynod/NALP10 Antibody

Novus Biologicals | Catalog # NBP2-24606

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Rabbit (95%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all NLRP10/Pynod/NALP10 Primary Antibodies »

Product Specifications

Immunogen

A portion of amino acids 493-509 of human NALP10 REVQRLLEVKEQEGNDE protein was used as the immunogen.

Reactivity Notes

The amino acid sequence used as immunogen is 95% homologous in rabbit and 86% homologous in mouse.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NLRP10/Pynod/NALP10 Antibody

Western Blot: NLRP10/Pynod/NALP10 Antibody [NBP2-24606]

Western Blot: NLRP10/Pynod/NALP10 Antibody [NBP2-24606]

Western Blot: NLRP10/Pynod/NALP10 Antibody [NBP2-24606] - Analysis of NALP10 in HeLa cell lysate in the 1) absence and 2) presence of immunizing peptide and 3) RAW cell lysate using NBP2-24606 at 1.0 ug/ml.

Applications for NLRP10/Pynod/NALP10 Antibody

Application
Recommended Usage

Western Blot

1.0-2.0 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NLRP10/Pynod/NALP10

Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminalleucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs tothe NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innateimmune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates thepro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as amultifunctional negative regulator of inflammation and apoptosis. (provided by RefSeq)

Long Name

NLR Family, Pyrin Domain Containing 10

Alternate Names

NALP10, NOD8, PAN5, Pynod

Gene Symbol

NLRP10

UniProt

Q86W26

Additional NLRP10/Pynod/NALP10 Products

Product Documents for NLRP10/Pynod/NALP10 Antibody

Certificate of Analysis

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Product Specific Notices for NLRP10/Pynod/NALP10 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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