NLRP11 Antibody - Azide and BSA Free

Novus Biologicals | Catalog # NBP2-93812

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

Azide and BSA Free
View all NLRP11 Primary Antibodies »

Product Specifications

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 420-600 of human NLRP11 (NP_659444.2). VGFTEADVSVLQAANILLPSNTHKDRYKFIHLNVQEFCTAIAFLMAVPNYLIPSGSREYKEKREQYSDFNQVFTFIFGLLNANRRKILETSFGYQLPMVDSFKWYSVGYMKHLDRDPEKLTHHMPLFYCLYENREEEFVKTIVDALMEVTVYLQSDKDMMVSLYCLDYCCHLRTLKLSVQR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NLRP11 Antibody - Azide and BSA Free

Western Blot: NLRP11 AntibodyAzide and BSA Free [NBP2-93812]

Western Blot: NLRP11 AntibodyAzide and BSA Free [NBP2-93812]

Western Blot: NLRP11 Antibody [NBP2-93812] - Analysis of extracts of 293T cells, using NLRP11 at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time:

Applications for NLRP11 Antibody - Azide and BSA Free

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol

Format

Azide and BSA Free

Preservative

0.01% Thimerosal

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: NLRP11

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP11, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM]

Alternate Names

CLR19.6, NACHT, leucine rich repeat and PYD containing 11, NALP11NACHT, LRR and PYD domains-containing protein 11, NLR family, pyrin domain containing 11, NOD17PYPAF7, Nucleotide-binding oligomerization domain protein 17, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domaincontaining 11, PAAD- and NACHT-containing protein 10, PAAD- and NACHT-containing protein 10B, PAAD-and NACHT domain-containing protein 10, PAN10FLJ26273, PYPAF6NACHT, LRR and PYD containing protein 11, PYRIN-containing APAF1-like protein 6

Gene Symbol

NLRP11

Additional NLRP11 Products

Product Documents for NLRP11 Antibody - Azide and BSA Free

Certificate of Analysis

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Product Specific Notices for NLRP11 Antibody - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including Methotrexate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

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