Non-Human Primate CXCL10/IP-10 Cartridge
R&D Systems | Catalog # SPCKB-NP-011473
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Key Product Details
Assay Length
Sample Type & Volume Required Per Well*
Sensitivity
Assay Range
Non-Human Primate CXCL10/IP-10 Cartridge Summary
*The Sample Volume represented is based on the amount of sample incorporated into the reaction after taking into account the assay's minimum required dilution for a given matrix. Serial dilution may be necessary to achieve some of the final sample volumes represented.
Compatible Instruments
Ella Automated Immunoassay System
Product Specifications
Assay Type
Format
Species
Specificity
Cross-reactivity
Interference
Precision
Intra-Assay Precision (Precision within an assay) Each control was tested 16 times in one assay.
Inter-Assay Precision (Precision between assays) Replicates of each control were tested in multiple assays performed by at least three technicians using two lots of reagents.
EDTA Plasma, Heparin Plasma, Serum
| Intra-Assay Precision | Inter-Assay Precision | |||
|---|---|---|---|---|
| Sample | 1 | 2 | 1 | 2 |
| n | 16 | 16 | 14 | 12 |
| Mean (pg/mL) | 5.65 | 283 | 5.49 | 297 |
| Standard Deviation | 0.347 | 14.3 | 0.212 | 11.7 |
| CV% | 6.1 | 5.0 | 3.9 | 3.9 |
Recovery for Non-Human Primate CXCL10/IP-10 Cartridge
Recovery was not necessary as IP-10 shows 5 points of natural linearity.
Linearity
Samples containing and/or spiked with high concentrations of IP-10 were serially diluted with Sample Diluent to produce samples within the dynamic range of the assay.
Scientific Data Images for Non-Human Primate CXCL10/IP-10 Cartridge
Non-Human Primate CXCL10/IP-10 Ella Assay Standard Curve
Preparation and Storage
Shipping
Stability & Storage
Background: CXCL10/IP-10/CRG-2
CXCL10/IP-10 is an ELR- angiostatic chemokine that interacts with CXCR3 to attract Th1 cells, eosinophils, monocytes, and NK cells to sites of inflammation. It is upregulated by activated T lymphocytes, neutrophils, splenocytes, keratinocytes, osteoblasts, astrocytes, endothelial cells, smooth muscle cells, and pancreatic beta cells. CXCL10 contributes to disease pathology in many chronic inflammatory disorders including rheumatoid arthritis, psoriasis, cancer, multiple sclerosis, diabetes, and cardiovascular disease.
Additional CXCL10/IP-10/CRG-2 Products
Product Documents for Non-Human Primate CXCL10/IP-10 Cartridge
Certificate of Analysis
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Product Specific Notices for Non-Human Primate CXCL10/IP-10 Cartridge
For research use only
Citations for Non-Human Primate CXCL10/IP-10 Cartridge
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