Chemical Name: 2-Amino-2-(2-chlorophenyl)cyclohexanone hydrochloride
Biological ActivityNorketamine hydrochloride is a major metabolite of ketamine that is a potent non-competitive NMDA receptor antagonist (Ki = 3.6 μM for displacement of [3H]-MK 801 in rat brain). Antinociceptive and anesthetic in vivo.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Comparative pharmacology in the rat of KA and its two principal metabolites, norKA and (Z)-6-hydroxynorKA.
Leung et al.
NorKA, the main metabolite of KA, is a non-competitive NMDA receptor antagonist in the rat cortex and spinal cord.
Ebert et al.
Oral KA is antinociceptive in the rat formalin test: role of the metabolite, norKA.
Shimoyama et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for Norketamine hydrochloride
There are currently no reviews for this product. Be the first to review Norketamine hydrochloride and earn rewards!
Have you used Norketamine hydrochloride?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image