NPEC-caged-(S)-AMPA

Tocris Bioscience | Catalog # 3840

Caged (S)-AMPA
Tocris Bioscience
Discontinued Product
3840 has been discontinued. View all AMPA Receptor Agonists products.

Key Product Details

Description

Caged (S)-AMPA
View all AMPA Receptor Agonists »

Product Description

NPEC-caged-(S)-AMPA is a 1-(2-nitrophenyl)ethyl caged version of (S)-AMPA (Cat. No. 0254), agonist at the AMPA receptor. Extinction coefficient (ε347) = 660 M-1cm-1, quantum yield (φ) = 0.64. Suitable for near-UV uncaging. No inhibition of GABA-A receptors at concentrations used experimentally.

Product Specifications for NPEC-caged-(S)-AMPA

Molecular Weight

379.32

Formula

C16H17N3O8

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

(N)-1-(2-Nitrophenyl)ethylcarboxy-(S)-α-1-(2-nitrophenyl)ethylcarboxyamino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

CAS Number

1257323-84-4

PubChem ID

90488885

InChI Key

LGVJRWDYNJZRRP-MYIOLCAUSA-N

SMILES

[H][C@@](NC(OC(C)C2=CC=CC=C2[N+]([O-])=O)=O)(C(O)=O)CC1=C(C)ON=C1O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 1.9 5 with gentle warming
DMSO 37.93 100

Preparing Stock Solutions for NPEC-caged-(S)-AMPA

The following data is based on the product molecular weight 379.32.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.64 mL 13.18 mL 26.36 mL
5 mM 0.53 mL 2.64 mL 5.27 mL
10 mM 0.26 mL 1.32 mL 2.64 mL
50 mM 0.05 mL 0.26 mL 0.53 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for NPEC-caged-(S)-AMPA

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for NPEC-caged-(S)-AMPA

For research use only

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