(S)-AMPA

Tocris Bioscience | Catalog # 0254

Selective AMPA agonist; active isomer of (RS)-AMPA (Cat. No. 0169)
Tocris Bioscience

Key Product Details

Description

Selective AMPA agonist; active isomer of (RS)-AMPA (Cat. No. 0169)
View all AMPA Receptor Agonists »

Product Description

(S)-AMPA is an active enantiomer of AMPA (EC50 = 3.5 μM).

NPEC-caged-(S)-AMPA, Inactive Enantiomer and Racemate also available.

Product Specifications for (S)-AMPA

Molecular Weight

186.17

Formula

C7H10N2O4

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

(S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

CAS Number

83643-88-3

PubChem ID

158397

InChI Key

UUDAMDVQRQNNHZ-YFKPBYRVSA-N

SMILES

[H][C@@](N)(C(O)=O)CC1=C(C)ON=C1O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 9.31 50

Preparing Stock Solutions for (S)-AMPA

The following data is based on the product molecular weight 186.17.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 10.74 mL 53.71 mL 107.43 mL
2.5 mM 2.15 mL 10.74 mL 21.49 mL
5 mM 1.07 mL 5.37 mL 10.74 mL
25 mM 0.21 mL 1.07 mL 2.15 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 91 publications citing the usage of this product.

Product Documents for (S)-AMPA

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (S)-AMPA

For research use only

Customer Reviews for (S)-AMPA (1)

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  • Test of AMPA effect on VGCCs-generated transmembrane current
    Name: Sergiy Sylantyev
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: Arcuate nucleus
    Verified Customer | Posted 12/10/2023
    10 μM AMPA was used to clarify the input of AMPA receptors into 5HT-1B receptors - activated modulation of voltage-gated calcium channel gating. Left: control. Right: the effect of activation of 5HT-1B and AMPA receptors on transmembrane current through VGCCs evoked upon membrane depolarization. Blue trace: control; red trace: 5HT-1B and AMPA receptors activation.
    (S)-AMPA 0254

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