-activated potassium (BKCa
1.1) channel activator. Induces a concentration-dependent decrease in mitochondrial membrane potential (EC50
= 3.6 μ
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All Tocris products are intended for laboratory research use only.
Selective activation of Ca(2+)-dependent K+ channels by novel benzimidazolone.
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Large-conductance K+ channel openers NS1619 and NS004 as inhibitors of mitochondrial function in glioma cells.
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The potassium ion channel opener NS1619 inhibits proliferation and induces apoptosis in A2780 ovarian cancer cells.
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