KDM4A/KDM4B inhibitor; inhibits histone demethylase activity on H3K9me3 and induces apoptosis in LNCaP prostate cancer cells in vitro
. Also negatively regulates androgen-responsive genes.
Soluble to 10 mM in DMSO
Store at +4°C
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All Tocris products are intended for laboratory research use only.
KDM4B as a target for prostate cancer: structural analysis and selective inhibition by a novel inhibitor.
Chu et al.