NVP 231

Catalog # Availability Size / Price Qty
NVP 231 | CAS No. 362003-83-6 | Other Kinase Inhibitors
1 Image
Description: Potent, selective and reversible CerK inhibitor

Chemical Name: N-[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[,7]decane-1-carboxamide

Purity: ≥98%

Product Details

Biological Activity

NVP 231 is a potent, selective and reversible ceramide kinase (CerK) inhibitor (IC50 = 12 nM in vitro). Displays selectivity for CerK over sphingosine kinases (IC50 ≥100 μM) and other lipid kinases.

Technical Data

Soluble to 100 mM in DMSO and to 5 mM in ethanol
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. A secondary assay for ceramide kinase inhibitors based on cell growth inhibition by short-chain ceramides.
    Graf et al.
    Anal.Biochem., 2009;384:166
  2. Ceramide kinase deficiency impairs microendothelial cell angiogenesis in vitro.
    Niwa et al.
    Microvasc.Res., 2009;77:389
  3. Targeting ceramide metabolism with a potent and specific ceramide kinase inhibitor.
    Graf et al.
    Mol.Pharmacol., 2009;74:925

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Molarity Calculator


*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).


No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for NVP 231

There are currently no reviews for this product. Be the first to review NVP 231 and earn rewards!

Have you used NVP 231?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.