NVS-CECR2-1

Tocris Bioscience | Catalog # 5744

Potent and selective CECR2 inhibitor
Tocris Bioscience

Key Product Details

Description

Potent and selective CECR2 inhibitor
View all Bromodomain Inhibitors »

Product Description

NVS-CECR2-1 is a potent and selective CECR2 (cat eye syndrome chromosome region, candidate 2) inhibitor (IC50 = 47 nM). Selective for CECR2 over a panel of bromodomains.

A concentration of 1 μM is recommended for use in cellular assays.

Licensing Information

This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the NVS-CECR2-1 probe summary on the SGC website.

Product Specifications for NVS-CECR2-1

Molecular Weight

495.68

Formula

C27H37N5O2S

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

N-Cyclopropyl-2-(propylsulfonyl)-6-(1-(2,2,6,6-tetramethylpiperidin-4-yl)-1H-indol-5-yl)pyrimidin-4-amine

CAS Number

1992047-61-6

PubChem ID

117072550

InChI Key

XVECNLUKQDKOST-UHFFFAOYSA-N

SMILES

CC(C1)(C)NC(C)(C)CC1N2C=CC3=C2C=CC(C4=NC(S(=O)(CCC)=O)=NC(NC5CC5)=C4)=C3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 49.57 100

Preparing Stock Solutions for NVS-CECR2-1

The following data is based on the product molecular weight 495.68.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.02 mL 10.09 mL 20.17 mL
5 mM 0.40 mL 2.02 mL 4.03 mL
10 mM 0.20 mL 1.01 mL 2.02 mL
50 mM 0.04 mL 0.20 mL 0.40 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

There are currently no references for this product.

Product Documents for NVS-CECR2-1

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for NVS-CECR2-1

For research use only

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