Obatoclax mesylate

Catalog # Availability Size / Price Qty
6539/10
6539/50
Cat.No. 6539 - Obatoclax mesylate | C20H19N3O.CH3SO3H | CAS No. 803712-79-0
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Description: Inhibitor of Bcl-2 family members; antiapoptotic
Alternative Names: GX15-070

Chemical Name: 2-[2-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene)-3-methoxy-2H-pyrrol-5-yl]-1H-indole methanesulfonate

Purity: ≥98%

Product Details
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Biological Activity

Inhibitor of Bcl-2 family members (IC50 values are 1.11 - 7 μM). Inhibits the interaction of a BH3 domain peptide with 6 members of the Bcl-2 family (Bcl-2, Bcl-XL, Mcl-1, Bcl-W, A1, and Bcl-B) in vitro. Has antiapoptotic and antitumor effects in several tumor bearing mouse models.

Technical Data

M.Wt:
413.49
Formula:
C20H19N3O.CH3SO3H
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
803712-79-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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