Antagonist of 5-HT2A
and dopamine D2
values are 4 and 11 nM respectively). Also displays affinity for a range of other receptors including D1
values range between 1.9 and 31 nM). Atypical antipsychotic. Displays anticholinergic properties.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
The behavioral pharmacology of olanzapine, a novel "atypical" antipsychotic agent.
Moore et al.
Radioreceptor binding profile of the atypical antipsychotic olanzapine.
Bymaster et al.
Olanzapine: preclinical and clinical profiles of a novel antipsychotic agent.
Tollefson and Taylor
CNS Drug Reviews, 2000;6:303
The citations listed below are publications that use Tocris products. Selected citations for Olanzapine include:
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